Tuticorin has various industries including power, chemicals, fisheries. Following are some of them:

• Tuticorin Thermal Power Station
• Sterlite Industries (India) Limited owned by Vedanta Resources
• SPIC fertilizer plant
• TAC fertilizer plant
• Darangadara Chemicals
• Kilburn Chemicals
• Madura Coats
• Transworld Garnet Industries
• VVD & Sons (P) Ltd (Manufacturers of ‘VVD Gold’ Coconut Oil)
• Heavy water Plant, Dept. of Atomic Energy
• Diamond Seafoods
• Nila Seafoods
• Ramesh Flowers
• Loyal Textiles